产品名称
MAGOH Rabbit Polyclonal Antibody (Center)
别名
Protein mago nashi homolog, MAGOH, MAGOHA
Human Gene ID
NP_002361.1
Human Swissprot No.
P61326
特异性
This MAGOH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 46-74 amino acids from the Central region of human MAGOH.
稀释度
WB~~1:1000;IHC-P~~1:100~500
背景介绍
Drosophila that have mutations in their mago nashi
(grandchildless) gene produce progeny with defects in germplasm
assembly and germline development. This gene encodes the mammalian
mago nashi homolog. In mammals, mRNA expression is not limited to
the germ plasm, but is expressed ubiquitously in adult tissues and
can be induced by serum stimulation of quiescent fibroblasts.
细胞定位
Nucleus. Nucleus speckle. Cytoplasm. Note=Detected in granule-like structures in the dendroplasm (By similarity). Travels to the cytoplasm as part of the exon junction complex (EJC) bound to mRNA. Colocalizes with the core EJC, ALYREF/THOC4, NXF1 and UAP56 in the nucleus and nuclear speckles (PubMed:19324961). {ECO:0000250, ECO:0000250|UniProtKB:Q27W02, ECO:0000269|PubMed:19324961}
纯化
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
