产品名称
WNT9B Rabbit Polyclonal Antibody
基因名称
WNT9B WNT14B WNT15 UNQ6973/PRO21956
蛋白名称
Protein Wnt-9b (Protein Wnt-14b) (Protein Wnt-15)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
O14905
Human Swissprot Link
https://www.uniprot.org/uniprotkb/O14905/entry
Mouse Swissprot No.
O35468
Mouse Swissprot Link
http://www.uniprot.org/uniprot/O35468
免疫原
Synthesized peptide derived from human protein . at AA range: 120-200
特异性
WNT9B Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
The WNT gene family consists of structurally related genes that encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. Study of its expression in the teratocarcinoma cell line NT2 suggests that it may be implicated in the early process of neuronal differentiation of NT2 cells induced by retinoic acid. This gene is clustered with WNT3, another family member, in the chromosome 17q21 region. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016],
组织表达
Moderately expressed in fetal kidney and adult kidney. Also found in brain.
细胞定位
Secreted, extracellular space, extracellular matrix . Secreted .
信号通路
WNT;WNT-T CELLHedgehog;Melanogenesis;Pathways in cancer;Basal cell carcinoma;
功能
function:Ligand for members of the frizzled family of seven transmembrane receptors.,function:Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters.,similarity:Belongs to the Wnt family.,tissue specificity:Moderately expressed in fetal kidney and adult kidney. Also found in brain.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
