BD-PB1321-OTU7B Rabbit Polyclonal Antibody (C-term)-现货抗体产品库武汉枢密脑科学技术有限公司

OTU7B Rabbit Polyclonal Antibody (C-term)

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产品基本信息

产品货号

BD-PB1321

产品名称

OTU7B Rabbit Polyclonal Antibody (C-term)

别名

OTU domain-containing protein 7B, Cellular zinc finger anti-NF-kappa-B protein, Zinc finger A20 domain-containing protein 1, Zinc finger protein Cezanne, OTUD7B, ZA20D1

类别

常规抗体

推荐应用

反应种属

Human

Human Gene ID

NP_064590.2

Human Swissprot No.

Q6GQQ9

特异性

This OTU7B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 757-784 amino acids from the C-terminal region of human OTU7B.

稀释度

WB~~1:1000;IHC-P~~1:100~500

预测分子量

93kDa

同种型

Rabbit Ig

背景介绍

OTU7B has deubiquitinating activity that is directed towards 'Lys-48' or 'Lys-63'-linked polyubiquitin chains. Hydrolyzes both linear and branched forms of polyubiquitin. Negative regulator of nuclear factor NF-kappa-B.

组织表达

Widely expressed. Abundant in kidney, heart and fetal liver. Expressed differentially among B-cells at distinct developmental stages. Higher expression seen in primary immature B- cells as compared to the mature cells.

细胞定位

Cytoplasm. Nucleus Note=Shuttles be cytoplasm and the nucleus in a XPO1/CRM1-dependent manner.

期货

现货

纯化

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

OTU7B Antibody (C-term) western blot analysis in MDA-MB453 cell line lysates (35ug/lane).This demonstrates the OTU7B antibody detected the OTU7B protein (arrow).

OTU7B Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.