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Mouse Matk Rabbit Polyclonal Antibody (C-term)

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产品基本信息

产品货号
BD-PB1315
产品名称
Mouse Matk Rabbit Polyclonal Antibody (C-term)
别名
Megakaryocyte-associated tyrosine-protein kinase, Protein kinase NTK, Tyrosine-protein kinase CTK, Matk, Ctk, Ntk
类别
常规抗体
推荐应用
WB
反应种属
Mouse
Human Swissprot No.
P41242
Mouse Gene ID
NP_034898.1
特异性
This Mouse Matk antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 477-505 amino acids from the C-terminal region of mouse Matk.
稀释度
WB~~1:1000;IHC-P~~1:100~500
预测分子量
56kDa
同种型
Rabbit Ig
背景介绍
Could play a significant role in the signal transduction of hematopoietic cells. May regulate tyrosine kinase activity of SRC-family members in brain by specifically phosphorylating their C-terminal regulatory tyrosine residue which acts as a negative regulatory site. It may play an inhibitory role in the control of T-cell proliferation.
组织表达
Most abundant in brain, and to a lesser extent in the spleen, the thymus and the liver. Also found in the T-cell lineage
细胞定位
Cytoplasm. Membrane. Note=In platelets, 90% of MATK localizes to the membrane fraction, and translocates to the cytoskeleton upon thrombin stimulation.
期货
现货
纯化
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Mouse Matk Antibody (C-term) western blot analysis in mouse spleen tissue lysates (35ug/lane).This demonstrates the Matk antibody detected the Matk protein (arrow).

Mouse Matk Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.

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