产品名称
Mouse Pdgfra Rabbit Polyclonal Antibody (Center)
别名
Platelet-derived growth factor receptor alpha, PDGF-R-alpha, PDGFR-alpha, Alpha platelet-derived growth factor receptor, Alpha-type platelet-derived growth factor receptor, CD140 antigen-like family member A, Platelet-derived growth factor alpha receptor, CD140a, Pdgfra
Human Swissprot No.
P26618
Mouse Gene ID
NP_001076785.1;NP_035188.2
特异性
This Mouse Pdgfra antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 678-706 amino acids from the Central region of mouse Pdgfra.
背景介绍
Receptor that binds both PDGFA and PDGFB and has a tyrosine-protein kinase activity.
组织表达
Focally expressed in cortical interstitial cells and highly expressed in the interstitium of the papillary region. Also expressed by adventitial cells in arterial vessels. Up-regulated in areas of renal fibrosis. In mice with unilateral ureteral obstruction, expression in cortical interstitial cells becomes prominent at day 4 which increases progressively until day 14
细胞定位
Cell membrane {ECO:0000250|UniProtKB:P16234}; Single-pass type I membrane protein {ECO:0000250|UniProtKB:P16234} Cell projection, cilium. Golgi apparatus
纯化
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
