产品名称
WNT8A Rabbit Polyclonal Antibody
蛋白名称
Protein Wnt-8a (Protein Wnt-8d)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q9H1J5
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9H1J5/entry
Mouse Swissprot No.
Q64527
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q64527
免疫原
Synthesized peptide derived from human protein . at AA range: 90-170
特异性
WNT8A Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family, and may be implicated in development of early embryos as well as germ cell tumors. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2014],
细胞定位
Secreted, extracellular space, extracellular matrix . Secreted .
信号通路
WNT;WNT-T CELLHedgehog;Melanogenesis;Pathways in cancer;Basal cell carcinoma;
功能
function:Ligand for members of the frizzled family of seven transmembrane receptors. May play an important role in the development and differentiation of certain forebrain structures, notably the hippocampus.,similarity:Belongs to the Wnt family.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
