产品名称
AGGF1 Rabbit Polyclonal Antibody (N-term)
别名
Angiogenic factor with G patch and FHA domains 1, Angiogenic factor VG5Q, hVG5Q, G patch domain-containing protein 7, Vasculogenesis gene on 5q protein, AGGF1, GPATC7, GPATCH7, VG5Q
Human Gene ID
NP_060516.2
Human Swissprot No.
Q8N302
特异性
This AGGF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 61-90 amino acids from the N-terminal region of human AGGF1.
背景介绍
This gene encodes an angiogenic factor that promotes
proliferation of endothelial cells. Mutations in this gene are
associated with a susceptibility to Klippel-Trenaunay syndrome.
Pseudogenes of this gene are found on chromosomes 3, 4, 10 and 16.
组织表达
Widely expressed. Expressed in endothelial cells, vascular smooth muscle cells and osteoblasts. Expressed in umbilical vein endothelial cells and microvascular endothelial cells
细胞定位
Cytoplasm. Secreted. Note=Cytoplasmic in microvascular endothelial cells. Upon angiogenesis, when endothelial cell tube formation is initiated, it is secreted
纯化
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
