产品名称
PRSS8 Rabbit Polyclonal Antibody (Center)
别名
Prostasin, 3421-, Channel-activating protease 1, CAP1, Serine protease 8, Prostasin light chain, Prostasin heavy chain, PRSS8
Human Gene ID
NP_002764.1
Human Swissprot No.
Q16651
特异性
This PRSS8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 190-219 amino acids from the Central region of human PRSS8.
背景介绍
This gene encodes a trypsinogen, which is a member of the
trypsin family of serine proteases. This enzyme is highly expressed
in prostate epithelia and is one of several proteolytic enzymes
found in seminal fluid. The proprotein is cleaved to produce a
light chain and a heavy chain which are associated by a disulfide
bond. It is active on peptide linkages involving the carboxyl group
of lysine or arginine.
组织表达
Found in prostate, liver, salivary gland, kidney, lung, pancreas, colon, bronchus and renal proximal tubular cells. In the prostate gland it may be synthesized in epithelial cells, secreted into the ducts, and excreted into the seminal fluid
细胞定位
[Prostasin]: Cell membrane; Single-pass membrane protein [Prostasin heavy chain]: Secreted, extracellular space. Note=Found in the seminal fluid. Secreted after cleavage of its C-terminus
纯化
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
