产品名称
WNT7B Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
P56706
Human Swissprot Link
https://www.uniprot.org/uniprotkb/P56706/entry
Mouse Swissprot No.
P28047
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P28047
免疫原
Synthesized peptide derived from human protein . at AA range: 110-190
特异性
WNT7B Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene is a member of the WNT gene family, which consists of structurally related genes that encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. Among members of the human WNT family, this gene product is most similar to WNT7A protein. [provided by RefSeq, Oct 2008],
组织表达
Moderately expressed in fetal brain, weakly expressed in fetal lung and kidney, and faintly expressed in adult brain, lung and prostate.
细胞定位
Secreted, extracellular space, extracellular matrix . Secreted .
信号通路
WNT;WNT-T CELLHedgehog;Melanogenesis;Pathways in cancer;Basal cell carcinoma;
功能
function:Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters.,similarity:Belongs to the Wnt family.,subunit:Interacts with PORCN.,tissue specificity:Moderately expressed in fetal brain, weakly expressed in fetal lung and kidney, and faintly expressed in adult brain, lung and prostate.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
