BD-PB1299-CIR Rabbit Polyclonal Antibody (N-term)-现货抗体产品库武汉枢密脑科学技术有限公司

CIR Rabbit Polyclonal Antibody (N-term)

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产品基本信息

产品货号

BD-PB1299

产品名称

CIR Rabbit Polyclonal Antibody (N-term)

别名

Corepressor interacting with RBPJ 1, CBF1-interacting corepressor, Recepin, CIR1, CIR

类别

常规抗体

推荐应用

反应种属

Human, Rat, Mouse

Human Gene ID

NP_004873.3

Human Swissprot No.

Q86X95

特异性

This CIR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 60-88 amino acids from the N-terminal region of human CIR.

稀释度

WB~~1:1000

预测分子量

52kDa

同种型

Rabbit Ig

背景介绍

CIR may modulate splice site selection during alternative splicing of pre-mRNAs. It fegulates transcription and acts as corepressor for RBPSUH. It recruits RBPSUH to the Sin3-histone deacetylase complex (HDAC) and is required for RBPSUH-mediated repression of transcription.

组织表达

Highly expressed in heart, brain, placenta, liver, skeletal muscle and pancreas.

细胞定位

Nucleus speckle. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Colocalizes with NEK6 in the centrosome

期货

现货

纯化

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

CIR Antibody (N-term) western blot analysis in THP-1 cell line,human placenta,rat heart and skeletal muscle lysates (35ug/lane).This demonstrates the CIR antibody detected the CIR protein (arrow).