BD-PB1294-Mouse Pxk Rabbit Polyclonal Antibody (Center)-现货抗体产品库武汉枢密脑科学技术有限公司

Mouse Pxk Rabbit Polyclonal Antibody (Center)

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产品基本信息

产品货号

BD-PB1294

产品名称

Mouse Pxk Rabbit Polyclonal Antibody (Center)

别名

PX domain-containing protein kinase-like protein, Modulator of Na,K-ATPase, MONaKA, Pxk {ECO:0000312|MGI:MGI:1289230}

类别

常规抗体

推荐应用

反应种属

Human, Mouse

Human Swissprot No.

Q8BX57

Mouse Gene ID

NP_663433.2;NP_840063.1

特异性

This Mouse Pxk antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 164-193 amino acids from the Central region of mouse Pxk.

稀释度

WB~~1:1000;IHC-P~~1:100~500

预测分子量

65kDa

同种型

Rabbit Ig

背景介绍

Pxk binds to and modulates brain Na,K-ATPase subunits ATP1B1 and ATP1B3 and may thereby participate in the regulation of electrical excitability and synaptic transmission. May not display kinase activity.

组织表达

Isoform 1 is present in all tissues examined. Isoform 2 is found in all tissues except skeletal muscle and very low levels in spleen. Both isoforms are widely expressed throughout the nervous system however levels of isoform 2 are higher in purified hippocampal and cortical neurons whereas glial cells express more isoform 1 than isoform 2.

细胞定位

Cytoplasm. Cell membrane; Peripheral membrane protein. Note=Also associates with the plasma membrane

期货

现货

纯化

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Mouse Pxk Antibody (Center) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the Pxk antibody detected the Pxk protein (arrow).

Western blot analysis of Pxk (arrow) using rabbit polyclonal Mouse Pxk Antibody (Center). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the Pxk gene.

Mouse Pxk Antibody (Center) western blot analysis in mouse brain tissue lysates (35ug/lane).This demonstrates the Pxk antibody detected the Pxk protein (arrow).

Mouse Pxk Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.