产品名称
RBM39 Rabbit Polyclonal Antibody (N-term)
别名
RNA-binding protein 39, CAPER alpha, Hepatocellular carcinoma protein 1, RNA-binding motif protein 39, RNA-binding region-containing protein 2, Splicing factor HCC1, RBM39, HCC1, RNPC2
Human Gene ID
NP_001229528.1;NP_001229529.1;NP_004893.1;NP_909122.1
Human Swissprot No.
Q14498
特异性
This RBM39 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 114-143 amino acids from the N-terminal region of human RBM39.
背景介绍
The protein encoded by this gene is an RNA binding protein
and possible splicing factor. The encoded protein is found in the
nucleus, where it colocalizes with core spliceosomal proteins.
Studies of a mouse protein with high sequence similarity to this
protein suggest that this protein may act as a transcriptional
coactivator for JUN/AP-1 and estrogen receptors. Multiple
transcript variants encoding different isoforms have been observed
for this gene.
组织表达
Widely expressed. Highly expressed in pancreas, skeletal muscle, lung and brain (PubMed:8227358). Expressed at intermediate level in kidney, liver and heart (PubMed:8227358)
细胞定位
Nucleus speckle. Note=Concentrated in nuclear speckles (PubMed:8227358). Colocalizes with the core spliceosomal snRNP proteins (PubMed:8227358)
纯化
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
