产品名称
SOCS6 Rabbit Polyclonal Antibody (N-term)
别名
Suppressor of cytokine signaling 6, SOCS-6, Cytokine-inducible SH2 protein 4, CIS-4, Suppressor of cytokine signaling 4, SOCS-4, SOCS6, CIS4, SOCS4
Human Gene ID
NP_004223.2
Human Swissprot No.
O14544
特异性
This SOCS6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 40-69 amino acids from the N-terminal region of human SOCS6.
稀释度
WB~~1:1000;IHC-P~~1:100~500
背景介绍
The protein encoded by this gene contains a SH2 domain and
a CIS homolog domain. The protein thus belongs to the
cytokine-induced STAT inhibitor (CIS), also known as suppressor of
cytokine signaling (SOCS) or STAT-induced STAT inhibitor (SSI),
protein family. CIS family members are known to be
cytokine-inducible negative regulators of cytokine signaling. The
expression of this gene can be induced by GM-CSF and EPO in
hematopoietic cells. A high expression level of this gene was found
in factor-independent chronic myelogenous leukemia (CML) and
erythroleukemia (HEL) cell lines.
纯化
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
