产品名称
SPN/CD43 Rabbit Polyclonal Antibody (Center)
别名
Leukosialin, Galactoglycoprotein, GALGP, Leukocyte sialoglycoprotein, Sialophorin, CD43, SPN, CD43
Human Gene ID
NP_001025459.1;NP_003114.1
Human Swissprot No.
P16150
特异性
This SPN/CD43 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 230-257 amino acids from the Central region of human SPN/CD43.
稀释度
WB~~1:1000;IHC-P~~1:100~500
背景介绍
Sialophorin (leukosialin) is a major sialoglycoprotein on
the surface of human T lymphocytes, monocytes, granulocytes, and
some B lymphocytes, which appears to be important for immune
function and may be part of a physiologic ligand-receptor complex
involved in T-cell activation.
组织表达
Cell surface of thymocytes, T-lymphocytes, neutrophils, plasma cells and myelomas
细胞定位
Membrane; Single-pass type I membrane protein. Cell projection, microvillus {ECO:0000250|UniProtKB:P13838}. Cell projection, uropodium {ECO:0000250|UniProtKB:P15702}. Note=Localizes to the uropodium and microvilli via its interaction with ERM proteins (EZR, RDX and MSN) {ECO:0000250|UniProtKB:P13838, ECO:0000250|UniProtKB:P15702}
纯化
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
