产品名称
DAO Rabbit Polyclonal Antibody (Center)
别名
D-amino-acid oxidase, DAAO, DAMOX, DAO, DAO, DAMOX
Human Gene ID
NP_001908.3
Human Swissprot No.
P14920
特异性
This DAO antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 259-287 amino acids from the Central region of human DAO.
背景介绍
This gene encodes the peroxisomal enzyme D-amino acid
oxidase. The enzyme is a flavoprotein which uses flavin adenine
dinucleotide (FAD) as its prosthetic group. Its substrates include
a wide variety of D-amino acids, but it is inactive on the
naturally occurring L-amino acids. Its biological function is not
known; it may act as a detoxifying agent which removes D-amino
acids that accumulate during aging. In mice, it degrades D-serine,
a co-agonist of the NMDA receptor. This gene may play a role in the
pathophysiology of schizophrenia.
纯化
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
