产品名称
Mouse Epha4 Rabbit Polyclonal Antibody (Center)
别名
Ephrin type-A receptor 4, Tyrosine-protein kinase receptor MPK-3, Tyrosine-protein kinase receptor SEK-1, Epha4, Sek, Sek1
Human Swissprot No.
Q03137
Mouse Gene ID
NP_031962.2
特异性
This Mouse Epha4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 464-492 amino acids from the Central region of mouse Epha4.
稀释度
WB~~1:1000;IHC-P~~1:100~500
背景介绍
Receptor for members of the ephrin-A family. Binds to ephrin-A1, -A4 and -A5. Binds more poorly to ephrin-A2 and -A3. May play a role in a signal transduction process involved in hindbrain pattern formation.
组织表达
Expressed in inner and outer pillar cells of the organ of Corti (at protein level) (PubMed:30639848). Highest expression in the adult brain and retina and also detectable in kidney, lung, skeletal muscle and thymus. Not detected in heart and liver. Expressed in myogenic progenitor cells (PubMed:27446912)
细胞定位
Cell membrane; Single-pass type I membrane protein. Cell projection, axon. Cell projection, dendrite. Cell junction, synapse, postsynaptic density membrane. Early endosome. Cell junction, adherens junction. Note=Clustered upon activation and targeted to early endosome
纯化
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
