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MMP28 Rabbit Polyclonal Antibody (Center)

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产品基本信息

产品货号
BD-PB1223
产品名称
MMP28 Rabbit Polyclonal Antibody (Center)
别名
Matrix metalloproteinase-28, MMP-28, 3424-, Epilysin, MMP28, MMP25
类别
常规抗体
推荐应用
WB
反应种属
Human
Human Gene ID
NP_001027449.1;NP_077278.1
Human Swissprot No.
Q9H239
特异性
This MMP28 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 195-223 amino acids from the Central region of human MMP28.
稀释度
WB~~1:1000;IHC-P~~1:100~500
预测分子量
59kDa
同种型
Rabbit Ig
背景介绍
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix for both normal physiological processes, such as embryonic development, reproduction and tissue remodeling, and disease processes, such as asthma and metastasis. This gene encodes a secreted enzyme that degrades casein. Its expression pattern suggests that it plays a role in tissue homeostasis and in wound repair. Transcript variants encoding different isoforms have been described. [provided by RefSeq].
组织表达
Expressed at high levels in testes and lung. Low levels are detected in kidney, pancreas and skin. Also expressed in fetal lung, brain, skeletal muscle and kidney. Expressed selectively in keratinocytes. Widely expressed in several carcinomas as well. Is up- regulated in response to injury in the skin
细胞定位
Secreted, extracellular space, extracellular matrix
期货
现货
纯化
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

MMP28 Antibody (Center) western blot analysis in MDA-MB435 cell line lysates (35ug/lane).This demonstrates the MMP28 antibody detected the MMP28 protein (arrow).

MMP28 Antibody (Center)immunohistochemistry analysis in formalin fixed and paraffin embedded human pancreas tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of MMP28 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.

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