产品名称
TIAM2 Rabbit Polyclonal Antibody (N-term)
别名
T-lymphoma invasion and metastasis-inducing protein 2, TIAM-2, SIF and TIAM1-like exchange factor, TIAM2, KIAA2016, STEF
Human Gene ID
NP_001010927.1;NP_036586.2
Human Swissprot No.
Q8IVF5
特异性
This TIAM2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 357-385 amino acids from the N-terminal region of human TIAM2.
背景介绍
This gene encodes a guanine nucleotide exchange factor. A
highly similar mouse protein specifically activates ras-related C3
botulinum substrate 1, converting this Rho-like guanosine
triphosphatase (GTPase) from a guanosine diphosphate-bound inactive
state to a guanosine triphosphate-bound active state. The encoded
protein may play a role in neural cell development. Alternatively
spliced transcript variants encoding different isoforms have been
described.
组织表达
Expressed in the occipital, frontal and temporal lobes, cerebellum, putamen and testis.
细胞定位
Cytoplasm {ECO:0000250|UniProtKB:Q6ZPF3}. Cell projection, lamellipodium {ECO:0000250|UniProtKB:Q6ZPF3}. Cell projection, filopodium {ECO:0000250|UniProtKB:Q6ZPF3}. Cell projection, growth cone {ECO:0000250|UniProtKB:Q6ZPF3}. Cell projection, neuron projection {ECO:0000250|UniProtKB:Q6ZPF3}. Perikaryon {ECO:0000250|UniProtKB:Q6ZPF3}
纯化
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
