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SELK Rabbit Polyclonal Antibody (Center)

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产品基本信息

产品货号
BD-PB1205
产品名称
SELK Rabbit Polyclonal Antibody (Center)
别名
Selenoprotein K, SelK, SELK
类别
常规抗体
推荐应用
WB
反应种属
Human, Rat, Mouse
Human Gene ID
NP_067060.2
Human Swissprot No.
Q9Y6D0
特异性
This SELK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 32-61 amino acids from the Central region of human SELK.
稀释度
WB~~1:500
预测分子量
11kDa
同种型
Rabbit Ig
背景介绍
This gene encodes a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. This selenoprotein is localized to the endoplasmic reticulum and is highly expressed in the heart, where it may function as an antioxidant.
组织表达
Highly expressed in heart.
细胞定位
Endoplasmic reticulum membrane; Single-pass membrane protein. Cell membrane; Single-pass membrane protein. Note=Probably mainly localized in the ER
期货
现货
纯化
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

All lanes : Anti-SELK Antibody (Center) at 1:500 dilution Lane 1: HepG2 whole cell lysate Lane 2: U-251 MG whole cell lysate Lane 3: PC-3 whole cell lysate Lane 4: NIH/3T3 whole cell lysate Lane 5: A20 whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 11 kDa Blocking/Dilution buffer: 5% NFDM/TBST.

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