产品名称
PPBN Rabbit Polyclonal Antibody
蛋白名称
Alkaline phosphatase, placental-like (EC 3.1.3.1) (ALP-1) (Alkaline phosphatase Nagao isozyme) (Germ cell alkaline phosphatase) (GCAP) (Placental alkaline phosphatase-like) (PLAP-like)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
P10696
Human Swissprot Link
https://www.uniprot.org/uniprotkb/P10696/entry
Mouse Swissprot No.
P24823
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P24823
免疫原
Synthesized peptide derived from human protein . at AA range: 10-90
特异性
PPBN Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The product of this gene is a membrane bound glycosylated enzyme, localized to testis, thymus and certain germ cell tumors, that is closely related to both the placental and intestinal forms of alkaline phosphatase. [provided by RefSeq, Jul 2008],
组织表达
Trace amounts in the testis and thymus, and in elevated amounts in germ cell tumors.
细胞定位
Cell membrane; Lipid-anchor, GPI-anchor.
信号通路
Folate biosynthesis;
功能
catalytic activity:A phosphate monoester + H(2)O = an alcohol + phosphate.,cofactor:Binds 1 magnesium ion.,cofactor:Binds 2 zinc ions.,miscellaneous:In most mammals there are four different isozymes: placental, placental-like, intestinal and tissue non-specific (liver/bone/kidney).,similarity:Belongs to the alkaline phosphatase family.,subunit:Homodimer.,tissue specificity:Trace amounts in the testis and thymus, and in elevated amounts in germ cell tumors.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
