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HNRNPH2 Rabbit Polyclonal Antibody (C-term)

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产品基本信息

产品货号
BD-PB1188
产品名称
HNRNPH2 Rabbit Polyclonal Antibody (C-term)
别名
Heterogeneous nuclear ribonucleoprotein H2, hnRNP H2, FTP-3, Heterogeneous nuclear ribonucleoprotein H', hnRNP H', Heterogeneous nuclear ribonucleoprotein H2, N-terminally processed, HNRNPH2, FTP3, HNRPH2
类别
常规抗体
推荐应用
WB
反应种属
Human
Human Gene ID
NP_001027565.1;NP_062543.1
Human Swissprot No.
P55795
特异性
This HNRNPH2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 311-340 amino acids from the C-terminal region of human HNRNPH2.
稀释度
WB~~1:1000
预测分子量
49kDa
同种型
Rabbit Ig
背景介绍
This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that binds to RNAs. It is very similar to the family member HNRPH1. This gene is thought to be involved in Fabray disease and X-linked agammaglobulinemia phenotype. Alternative splicing results in multiple transcript variants encoding the same protein.
组织表达
Expressed ubiquitously.
细胞定位
Nucleus, nucleoplasm.
期货
现货
纯化
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

All lanes: Anti-HNRNPH2 Antibody (C-term) at 1:1000 dilution Lane 1: U-251 MG whole cell lysate Lane 1: rat heart lysate Lysates/proteins at 20 µg per lane. Secondary: Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/15000 dilution. Observed band size: 50KDa Blocking/Dilution buffer: 5% NFDM/TBST.

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