BD-PB1181-PHF17 Rabbit Polyclonal Antibody (N-term)-现货抗体产品库武汉枢密脑科学技术有限公司

PHF17 Rabbit Polyclonal Antibody (N-term)

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产品基本信息

产品货号

BD-PB1181

产品名称

PHF17 Rabbit Polyclonal Antibody (N-term)

别名

Protein Jade-1, Jade family PHD finger protein 1, PHD finger protein 17, JADE1, KIAA1807, PHF17

类别

常规抗体

推荐应用

反应种属

Human

Human Gene ID

NP_079176.2;NP_955352.1

Human Swissprot No.

Q6IE81

特异性

This PHF17 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 22-51 amino acids from the N-terminal region of human PHF17.

稀释度

WB~~1:1000;IHC-P~~1:100~500

预测分子量

96kDa

同种型

Rabbit Ig

背景介绍

Component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. Transcriptional coactivator it may also promote acetylation of nucleosomal histone H4 by KAT5. Promotes apoptosis. May act as a renal tumor suppressor.

组织表达

Highly expressed in kidney. Also present in pancreas, liver and heart (at protein level). Down-regulated in renal cancer cells.

细胞定位

Nucleus. Chromosome Cytoplasm Cytoplasm, cytoskeleton, cilium basal body. Note=Localizes to the ciliary transition zone.

期货

现货

纯化

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Western blot analysis of lysate from U-251 MG cell line, using PHF17 Antibody (N-term)at 1:5000 dilution was used as the secondary antibody. Lysate at 35ug per lane.

PHF17 Antibody (N-term)immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of PHF17 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.