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SLIT1 Rabbit Polyclonal Antibody (N-term)

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产品基本信息

产品货号
BD-PB1179
产品名称
SLIT1 Rabbit Polyclonal Antibody (N-term)
别名
Slit homolog 1 protein, Slit-1, Multiple epidermal growth factor-like domains protein 4, Multiple EGF-like domains protein 4, SLIT1, KIAA0813, MEGF4, SLIL1
类别
常规抗体
推荐应用
WB
反应种属
Mouse
Human Gene ID
NP_003052.2
Human Swissprot No.
O75093
特异性
This SLIT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 84-113 amino acids from the N-terminal region of human SLIT1.
稀释度
WB~~1:1000;IHC-P~~1:100~500
预测分子量
168kDa
同种型
Rabbit Ig
背景介绍
Thought to act as molecular guidance cue in cellular migration, and function appears to be mediated by interaction with roundabout homolog receptors. During neural development involved in axonal navigation at the ventral midline of the neural tube and projection of axons to different regions (By similarity). SLIT1 and SLIT2 together seem to be essential for midline guidance in the forebrain by acting as repulsive signal preventing inappropriate midline crossing by axons projecting from the olfactory bulb.
组织表达
Predominantly expressed in adult forebrain. Expressed in fetal brain, lung and kidney
细胞定位
Secreted.
期货
现货
纯化
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

SLIT1 Antibody (N-term) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the SLIT1 antibody detected the SLIT1 protein (arrow).

SLIT1 Antibody (N-term)immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of SLIT1 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.

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