产品名称
PDCD2 Rabbit Polyclonal Antibody
蛋白名称
Programmed cell death protein 2 (Zinc finger MYND domain-containing protein 7) (Zinc finger protein Rp-8)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q16342
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q16342/entry
Mouse Swissprot No.
P46718
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P46718
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941P47816
免疫原
Synthesized peptide derived from human protein . at AA range: 180-260
特异性
PDCD2 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a nuclear protein expressed in a variety of tissues. Expression of this gene has been shown to be repressed by B-cell CLL/lymphoma 6 (BCL6), a transcriptional repressor required for lymph node germinal center development, suggesting that BCL6 regulates apoptosis by its effects on this protein. Alternative splicing results in multiple transcript variants and pseudogenes have been identified on chromosomes 9 and 12. [provided by RefSeq, Dec 2010],
功能
function:May be a DNA-binding protein with a regulatory function. May play an important role in cell death and/or in regulation of cell proliferation.,similarity:Contains 1 MYND-type zinc finger.,tissue specificity:Ubiquitous.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.