产品名称
GRHL2 Rabbit Polyclonal Antibody (Center)
别名
Grainyhead-like protein 2 homolog, Brother of mammalian grainyhead, Transcription factor CP2-like 3, GRHL2, BOM, TFCP2L3
Human Gene ID
NP_079191.2
Human Swissprot No.
Q6ISB3
特异性
This GRHL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 409-438 amino acids from the Central region of human GRHL2.
背景介绍
The protein encoded by this gene is a transcription factor
that can act as a homodimer or as a heterodimer with either GRHL1
or GRHL3. Defects in this gene are a cause of non-syndromic
sensorineural deafness autosomal dominant type 28 (DFNA28).
组织表达
Expressed in keratinocytes (at protein level). Highly expressed in placenta, prostate, brain and kidney. Lower-level expression in a variety of epithelial tissues such as thymus, lung, salivary gland, mammary gland and digestive tract. Expressed in the cochlear. Expressed in corneal epithelial cells, but not in the endothelium or stroma (PubMed:29499165).
细胞定位
Nucleus. Membrane. Note=detected at cell-cell contact areas.
纯化
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
