BD-PB1125

KREMEN2 Rabbit Polyclonal Antibody (Center)

Kremen protein 2, Dickkopf receptor 2, Kringle domain-containing transmembrane protein 2, Kringle-containing protein marking the eye and the nose, KREMEN2, KRM2

常规抗体

WB

Human

NP_001240654.1;NP_001240655.1;NP_078783.1;NP_757384.1

Q8NCW0

This KREMEN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 248-276 amino acids from the Central region of human KREMEN2.

WB~~1:1000

49kDa

Rabbit Ig

This gene encodes a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor that functionally cooperates with DKK1 to block wingless (WNT)/beta-catenin signaling. The encoded protein forms a ternary membrane complex with DKK1 and the WNT receptor lipoprotein receptor-related protein 6 (LRP6), and induces rapid endocytosis and removal of LRP6 from the plasma membrane. It contains extracellular kringle, WSC, and CUB domains. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene.

Membrane; Single-pass type I membrane protein

现货

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.