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HPSE2 Rabbit Polyclonal Antibody (C-term)

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产品基本信息

产品货号
BD-PB1113
产品名称
HPSE2 Rabbit Polyclonal Antibody (C-term)
别名
Inactive heparanase-2, Hpa2, HPSE2, HPA2
类别
常规抗体
推荐应用
WB
反应种属
Human, Mouse
Human Gene ID
NP_001159716.1;NP_001159717.1;NP_001159718.1;NP_068600.4
Human Swissprot No.
Q8WWQ2
特异性
This HPSE2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 451-480 amino acids from the C-terminal region of human HPSE2.
稀释度
WB~~1:1000;IHC-P~~1:100~500
预测分子量
67kDa
同种型
Rabbit Ig
背景介绍
Endoglycosidase which is a cell surface and extracellular matrix-degrading enzyme. Cleaves heparan sulfate proteoglycans (HSPGs) into heparan sulfate side chains and core proteoglycans. Also implicated in the extravasation of leukocytes and tumor cell lines. Due to its contribution to metastasis and angiogenesis, it is considered to be a potential target for anti-cancer therapies.
组织表达
Widely expressed, with the highest expression in brain, mammary gland, prostate, small intestine, testis and uterus. In the central nervous system, expressed in the spinal chord, caudate nucleus, thalamus, substantia nigra, medulla oblongata, putamen and pons. In the urinary bladder, expressed in longitudinal and circular layers of detrusor muscle. Found both in normal and cancer tissues
细胞定位
Secreted, extracellular space, extracellular matrix
期货
现货
纯化
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Western blot analysis of lysates from HeLa, Jurkat cell line (from left to right), using HPSE2 Antibody (C-term)at 1:5000 dilution was used as the secondary antibody. Lysates at 35ug per lane.

HPSE2 Antibody (C-term)immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of HPSE2 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.

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