BD-PB1105-IRAK4 Rabbit Polyclonal Antibody (N-term)-现货抗体产品库武汉枢密脑科学技术有限公司

IRAK4 Rabbit Polyclonal Antibody (N-term)

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产品基本信息

产品货号

BD-PB1105

产品名称

IRAK4 Rabbit Polyclonal Antibody (N-term)

别名

Interleukin-1 receptor-associated kinase 4, IRAK-4, Renal carcinoma antigen NY-REN-64, IRAK4

类别

常规抗体

推荐应用

反应种属

Human

Human Gene ID

NP_001107654.1;NP_001138728.1;NP_001138729.1;NP_001138730.1;NP_057207.2

Human Swissprot No.

Q9NWZ3

特异性

This IRAK4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 25-52 amino acids from the N-terminal region of human IRAK4.

稀释度

WB~~1:1000

预测分子量

52kDa

同种型

Rabbit Ig

背景介绍

This gene encodes a kinase that activates NF-kappaB in both the Toll-like receptor (TLR) and T-cell receptor (TCR) signaling pathways. The protein is essential for most innate immune responses. Mutations in this gene result in IRAK4 deficiency and recurrent invasive pneumococcal disease. Multiple transcript variants encoding different isoforms have been found for this gene.

细胞定位

Cytoplasm.

期货

现货

纯化

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Anti-IRAK4 Antibody (N-term) at 1:1000 dilution + K562 whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 52 kDa Blocking/Dilution buffer: 5% NFDM/TBST.

IRAK4 Antibody (N-term) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the IRAK4 antibody detected the IRAK4 protein (arrow).