产品名称
RBM28 Rabbit Polyclonal Antibody (N-term)
别名
RNA-binding protein 28, RNA-binding motif protein 28, RBM28
Human Gene ID
NP_001159607.1;NP_060547.2
Human Swissprot No.
Q9NW13
特异性
This RBM28 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 62-91 amino acids from the N-terminal region of human RBM28.
背景介绍
The protein encoded by this gene is a specific nucleolar
component of the spliceosomal small nuclear ribonucleoprotein
(snRNP)complexes . It specifically associates with U1, U2, U4, U5,
and U6 small nuclear RNAs (snRNAs), possibly coordinating their
transition through the nucleolus. Mutation in this gene causes
alopecia, progressive neurological defects, and endocrinopathy (ANE
syndrome), a pleiotropic and clinically heterogeneous disorder.
Alternatively spliced transcript variants encoding different
isoforms have been found for this gene.
组织表达
Ubiquitously expressed.
细胞定位
Nucleus, nucleolus {ECO:0000269|PubMed:12429849, ECO:0000269|PubMed:17081119, ECO:0000269|Ref.7}
纯化
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
