BD-PB1078-RIC3 Rabbit Polyclonal Antibody (C-term)-现货抗体产品库武汉枢密脑科学技术有限公司

RIC3 Rabbit Polyclonal Antibody (C-term)

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产品基本信息

产品货号

BD-PB1078

产品名称

RIC3 Rabbit Polyclonal Antibody (C-term)

别名

Protein RIC-3, Resistant to inhibitor of cholinesterase 3, RIC3

类别

常规抗体

推荐应用

反应种属

Human

Human Gene ID

NP_001128581.1;NP_001193600.1;NP_001193601.1;NP_078833.3

Human Swissprot No.

Q7Z5B4

特异性

This RIC3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 313-341 amino acids from the C-terminal region of human RIC3.

稀释度

IHC-P~~1:100~500;WB~~1:1000

预测分子量

41kDa

同种型

Rabbit Ig

背景介绍

RIC3 is a protein associated with nicotinic acetylcholine receptors (nAChRs), neurotransmitter-gated ion channels expressed at the neuromuscular junction and within the central and peripheral nervous systems, that can enhance functional expression of multiple nAChR subtypes (Lansdell et al., 2005 [PubMed 16120769]).[supplied by OMIM].

组织表达

Broadly expressed, with high levels in muscle, brain, heart, pancreas and testis. In the central nervous system, highest levels are detected in the cerebellum and pituitary gland Over-expressed in brains from patients with bipolar disease or schizophrenia. Isoform 5 is predominantly expressed in the brain

细胞定位

[Isoform 1]: Endoplasmic reticulum membrane; Single-pass membrane protein

期货

现货

纯化

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

RIC3 Antibody (C-term)immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of RIC3 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.

RIC3 Antibody (C-term) western blot analysis in NCI-H292,A549,WiDr,MDA-MB453 cell line lysates (35ug/lane).This demonstrates the RIC3 antibody detected the RIC3 protein (arrow).