产品名称
HIST1H2BO/HIST1H2BH Rabbit Polyclonal Antibody (N-term)
别名
Histone H2B type 1-O, Histone H2B2, Histone H2Bn, H2B/n, HIST1H2BO, H2BFH, H2BFN
Human Gene ID
NP_003518.2
Human Swissprot No.
P23527
特异性
This HIST1H2BO/HIST1H2BH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human HIST1H2BO/HIST1H2BH.
背景介绍
Histones are basic nuclear proteins that are responsible
for the nucleosome structure of the chromosomal fiber in
eukaryotes. Two molecules of each of the four core histones (H2A,
H2B, H3, and H4) form an octamer, around which approximately 146 bp
of DNA is wrapped in repeating units, called nucleosomes. The
linker histone, H1, interacts with linker DNA between nucleosomes
and functions in the compaction of chromatin into higher order
structures. This gene is intronless and encodes a member of the
histone H2B family. Transcripts from this gene lack polyA tails but
instead contain a palindromic termination element. This gene is
found in the small histone gene cluster on chromosome 6p22-p21.3.
细胞定位
Nucleus. Chromosome.
纯化
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
