产品名称
KIF15 Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/56992
Human Swissprot No.
Q9NS87
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9NS87/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/209737
Mouse Swissprot No.
Q6P9L6
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q6P9L6
Rat Gene Link
https://www.uniprot.org/uniprot/353302
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q7TSP2
免疫原
Synthesized peptide derived from human KIF15 AA range: 974-1024
特异性
This antibody detects endogenous levels of KIF15 at Human/Mouse/Rat
宿主
Polyclonal, Rabbit,IgG
组织表达
Expressed in testis, colon, thymus and in breast cancer.
细胞定位
Cytoplasm. Cytoplasm, cytoskeleton, spindle. Detected during the interphase in the cytoplasm as finely punctuate pattern and irregularly shaped dots. Detected during mitosis on the mitotic spindle. Colocalizes with TPX2 in mitosis. Localizes at the central spindle at anaphase (By similarity). Localizes at the sites of invaginating cell membranes, a position that corresponds to the location of the contractile actomyosin ring of dividing cells (By similarity). Colocalizes with actin in interphase (By similarity). Colocalizes in dendrites and in growth cone of axons with microtubules (By similarity). .
功能
function:Plus-end directed kinesin-like motor enzyme involved in mitotic spindle assembly.,similarity:Belongs to the kinesin-like protein family. KLP2 subfamily.,similarity:Contains 1 kinesin-motor domain.,subcellular location:Detected during the interphase in the cytoplasm as finely punctuate pattern and irregularly shaped dots. Detected during mitosis on the mitotic spindle. Colocalizes with TPX2 in mitosis. Localizes at the central spindle at anaphase (By similarity). Localizes at the sites of invaginating cell membranes, a position that corresponds to the location of the contractile actomyosin ring of dividing cells (By similarity). Colocalizes with actin in interphase (By similarity). Colocalizes in dendrites and in growth cone of axons with microtubules.,subunit:Interacts with MKI67 and TPX2.,tissue specificity:Expressed in testis, colon, tymus and in breast cancer.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
