BD-PB1041-POMT1 Rabbit Polyclonal Antibody (C-term)-现货抗体产品库武汉枢密脑科学技术有限公司

POMT1 Rabbit Polyclonal Antibody (C-term)

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产品基本信息

产品货号

BD-PB1041

产品名称

POMT1 Rabbit Polyclonal Antibody (C-term)

别名

Protein O-mannosyl-transferase 1, Dolichyl-phosphate-mannose--protein mannosyltransferase 1, POMT1

类别

常规抗体

推荐应用

反应种属

Human

Human Gene ID

NP_001070833.1;NP_001070834.1;NP_001129585.1;NP_001129586.1;NP_009102.3

Human Swissprot No.

Q9Y6A1

特异性

This POMT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 706-735 amino acids from the C-terminal region of human POMT1.

稀释度

IHC-P~~1:100~500;WB~~1:1000;FC~~1:10~50

预测分子量

85kDa

同种型

Rabbit Ig

背景介绍

The protein encoded by this gene is an O-mannosyltransferase that requires interaction with the product of the POMT2 gene for enzymatic function. The encoded protein is found in the membrane of the endoplasmic reticulum. Defects in this gene are a cause of Walker-Warburg syndrome (WWS) and limb-girdle muscular dystrophy type 2K (LGMD2K). Several transcript variants encoding different isoforms have been found for this gene.

组织表达

Widely expressed. Highly expressed in testis, heart and pancreas. Detected at lower levels in kidney, skeletal muscle, brain, placenta, lung and liver

细胞定位

Endoplasmic reticulum membrane; Multi-pass membrane protein

期货

现货

纯化

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

POMT1 Antibody (C-term)immunohistochemistry analysis in formalin fixed and paraffin embedded human testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of POMT1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.

POMT1 Antibody (C-term) western blot analysis in ZR-75-1,K562 cell line lysates (35ug/lane).This demonstrates the POMT1 antibody detected the POMT1 protein (arrow).

POMT1 Antibody (C-term) flow cytometric analysis of U251 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.