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COX6B1 Rabbit Polyclonal Antibody (C-term)

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产品基本信息

产品货号
BD-PB1033
产品名称
COX6B1 Rabbit Polyclonal Antibody (C-term)
别名
Cytochrome c oxidase subunit 6B1, Cytochrome c oxidase subunit VIb isoform 1, COX VIb-1, COX6B1, COX6B
类别
常规抗体
推荐应用
WB
反应种属
Human
Human Gene ID
NP_001854.1
Human Swissprot No.
P14854
特异性
This COX6B1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 59-86 amino acids from the C-terminal region of human COX6B1.
稀释度
WB~~1:1000;IHC-P~~1:100~500
预测分子量
10kDa
同种型
Rabbit Ig
背景介绍
Cytochrome c oxidase (COX), the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may be involved in the regulation and assembly of the complex. This nuclear gene encodes subunit VIb. Mutations in this gene are associated with severe infantile encephalomyopathy. Three pseudogenes COX6BP-1, COX6BP-2 and COX6BP-3 have been found on chromosomes 7, 17 and 22q13.1-13.2, respectively.
细胞定位
Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side
期货
现货
纯化
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

COX6B1 Antibody (C-term) western blot analysis in ZR-75-1,A549,NCI-H292 cell line lysates (35ug/lane).This demonstrates the COX6B1 antibody detected the COX6B1 protein (arrow).

COX6B1 Antibody (C-term)immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of COX6B1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.

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