产品名称
MAGE1 Rabbit Polyclonal Antibody
基因名称
MAGEE1 HCA1 KIAA1587
蛋白名称
Melanoma-associated antigen E1 (Alpha-dystrobrevin-associated MAGE Protein) (DAMAGE) (Hepatocellular carcinoma-associated protein 1) (MAGE-E1 antigen)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q9HCI5
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9HCI5/entry
Mouse Swissprot No.
Q6PCZ4
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q6PCZ4
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941A1A5P9
免疫原
Synthesized peptide derived from human protein . at AA range: 760-840
特异性
MAGE1 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes an alpha-dystrobrevin-associated MAGE (melanoma-associated antigen) protein, which is a member of the MAGE family. The protein contains a nuclear localization signal in the N-terminus, 30 12-amino acid repeats beginning at nt 60 with the consensus sequence ASEGPSTSVLPT, and two MAGE domains in the C-terminus. It may play a signaling role in brain, muscle, and peripheral nerve. This gene is located on X chromosome in a region containing loci linked to mental retardation. [provided by RefSeq, Mar 2010],
细胞定位
Cytoplasm, perinuclear region . Nucleus . Cell membrane . In the skeletal muscle, found at the postsynaptic membrane and is associated with a subset of myonuclei. May reside within nuclei and/or in perinuclear compartments. In peripheral nerves, colocalizes with DTNA in the Schwann cell membrane (By similarity). .
功能
similarity:Contains 2 MAGE domains.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.