BD-PB1012-VSNL1 Rabbit Polyclonal Antibody (Center)-现货抗体产品库武汉枢密脑科学技术有限公司

VSNL1 Rabbit Polyclonal Antibody (Center)

产品详情相关文献产品问答相关产品

产品基本信息

产品货号

BD-PB1012

产品名称

VSNL1 Rabbit Polyclonal Antibody (Center)

别名

Visinin-like protein 1, VILIP, VLP-1, Hippocalcin-like protein 3, HLP3, VSNL1, VISL1

类别

常规抗体

推荐应用

反应种属

Human, Mouse

Human Gene ID

NP_003376.2

Human Swissprot No.

P62760

特异性

This VSNL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 47-75 amino acids from the Central region of human VSNL1.

稀释度

WB~~1:1000;IHC-P~~1:100~500;FC~~1:10~50

预测分子量

22kDa

同种型

Rabbit Ig

背景介绍

This gene is a member of the visinin/recoverin subfamily of neuronal calcium sensor proteins. The encoded protein is strongly expressed in granule cells of the cerebellum where it associates with membranes in a calcium-dependent manner and modulates intracellular signaling pathways of the central nervous system by directly or indirectly regulating the activity of adenylyl cyclase. Alternatively spliced transcript variants have been observed, but their full-length nature has not been determined.

组织表达

Brain and retina. Neuron-specific in the central and peripheral nervous system. Increased in the cerebrospinal fluid of Alzheimer disease patients (at protein level)

期货

现货

纯化

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Western blot analysis of VSNL1 (arrow) using rabbit polyclonal VSNL1 Antibody (Center). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the VSNL1 gene.

VSNL1 Antibody (Center) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the VSNL1 antibody detected the VSNL1 protein (arrow).

VSNL1 Antibody (Center)immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of VSNL1 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.

VSNL1 Antibody (Center) flow cytometric analysis of 293 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.