BD-PB1011-PRMT8 Rabbit Polyclonal Antibody (C-term)-现货抗体产品库武汉枢密脑科学技术有限公司

PRMT8 Rabbit Polyclonal Antibody (C-term)

产品详情相关文献产品问答相关产品

产品基本信息

产品货号

BD-PB1011

产品名称

PRMT8 Rabbit Polyclonal Antibody (C-term)

别名

Protein arginine N-methyltransferase 8, 211-, Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 4, PRMT8, HRMT1L3, HRMT1L4

类别

常规抗体

推荐应用

反应种属

Human, Rat, Mouse

Human Gene ID

NP_001243465.1;NP_062828.3

Human Swissprot No.

Q9NR22

特异性

This PRMT8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 344-373 amino acids from the C-terminal region of human PRMT8.

稀释度

WB~~1:1000

预测分子量

45kDa

同种型

Rabbit Ig

背景介绍

Protein arginine methylation plays a role in signal transduction, RNA processing, transcriptional regulation, and DNA repair. PRMT8, a protein arginine N-methyltransferase most closely related to PRMT1, methylates the guanidino nitrogens of arginyl residues in some proteins. This protein associates with the plasma membrane following myristoylation and exhibits a brain-specific expression pattern, making it unique within this family of enzymes.

组织表达

Brain-specific..

细胞定位

Cell membrane; Lipid-anchor; Cytoplasmic side

期货

现货

纯化

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Western blot analysis of lysates from human brain, mouse brain tissue lysate (from left to right), using PRMT8 Antibody (C-term). BD-PB1011 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysates at 35ug per lane.

Western blot analysis of PRMT8 Antibody (C-term) in K562 cell line lysates (35ug/lane). PRMT8 (arrow) was detected using the purified Pab.

Western blot analysis of PRMT8 (arrow) using rabbit polyclonal PRMT8 Antibody (C-term) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the PRMT8 gene (Lane 2) .