BD-PB1007-TTBK2 Rabbit Polyclonal Antibody (N-term)-现货抗体产品库武汉枢密脑科学技术有限公司

TTBK2 Rabbit Polyclonal Antibody (N-term)

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产品基本信息

产品货号

BD-PB1007

产品名称

TTBK2 Rabbit Polyclonal Antibody (N-term)

别名

Tau-tubulin kinase 2, TTBK2, KIAA0847

类别

常规抗体

推荐应用

反应种属

Human

Human Gene ID

NP_775771.3

Human Swissprot No.

Q6IQ55

特异性

This TTBK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 217-245 amino acids from the N-terminal region of human TTBK2.

稀释度

WB~~1:1000;IHC-P~~1:100~500;FC~~1:10~50

预测分子量

137kDa

同种型

Rabbit Ig

背景介绍

This gene encodes a serine-threonine kinase that putatively phosphorylates tau and tubulin proteins. Mutations in this gene cause spinocerebellar ataxia type 11 (SCA11); a neurodegenerative disease characterized by progressive ataxia and atrophy of the cerebellum and brainstem.

细胞定位

Cell projection, cilium. Cytoplasm, cytoskeleton, cilium basal body. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, cytosol. Nucleus. Note=Localizes to the transition zone in primary cilia in response to cell cycle signals that promote ciliogenesis (By similarity). May also be present in cytosol and, at lower level in the nucleus.

期货

现货

纯化

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

TTBK2 Antibody (N-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the TTBK2 antibody detected the TTBK2 protein (arrow).

TTBK2 Antibody (N-term)immunohistochemistry analysis in formalin fixed and paraffin embedded human lung tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of TTBK2 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.

TTBK2 Antibody (N-term) flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.