BD-PB1000-TXNL2 Rabbit Polyclonal Antibody (N-term)-现货抗体产品库武汉枢密脑科学技术有限公司

TXNL2 Rabbit Polyclonal Antibody (N-term)

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产品基本信息

产品货号

BD-PB1000

产品名称

TXNL2 Rabbit Polyclonal Antibody (N-term)

别名

Glutaredoxin-3, PKC-interacting cousin of thioredoxin, PICOT, PKC-theta-interacting protein, PKCq-interacting protein, Thioredoxin-like protein 2, GLRX3, PICOT, TXNL2

类别

常规抗体

推荐应用

反应种属

Human, Mouse

Human Gene ID

NP_001186797.1;NP_006532.2

Human Swissprot No.

O76003

特异性

This TXNL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 81-110 amino acids from the N-terminal region of human TXNL2.

稀释度

WB~~1:1000;FC~~1:10~50

预测分子量

37kDa

同种型

Rabbit Ig

背景介绍

GLRX3 is a critical negative regulator of cardiac hypertrophy and a positive inotropic regulator (By similarity). May play a role in regulating the function of the thioredoxin system. Does not posses any thyoredoxin activity since it lacks the conserved motif that is essential for catalytic activity.

组织表达

Expressed in heart, spleen, testis and, to a lower extent, in thymus and peripheral blood leukocytes. Weakly expressed in lung, placenta, colon and small intestine

细胞定位

Cytoplasm, cytosol. Cytoplasm, cell cortex. Cytoplasm, myofibril, sarcomere, Z line {ECO:0000250|UniProtKB:Q9CQM9}. Note=Under the plasma membrane (By similarity). After PMA stimulation, GLRX3 and PRKCQ/PKC-theta translocate to a more extended submembrane area (By similarity). In the Z line, found associated with CSRP3 (By similarity). {ECO:0000250|UniProtKB:Q9CQM9}

期货

现货

纯化

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

All lanes : Anti-TXNL2 Antibody (N-term) at 1:1000 dilution Lane 1: HepG2 whole cell lysate Lane 2: Raji whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 37 kDa Blocking/Dilution buffer: 5% NFDM/TBST.

TXNL2 Antibody (N-term) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the TXNL2 antibody detected the TXNL2 protein (arrow).

TXNL2 Antibody (N-term) western blot analysis in mouse bladder tissue lysates (35ug/lane).This demonstrates the TXNL2 antibody detected the TXNL2 protein (arrow).

TXNL2 Antibody (N-term) flow cytometric analysis of HepG2 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.