BD-PB0999-ZMYND10 Rabbit Polyclonal Antibody (Center)-现货抗体产品库武汉枢密脑科学技术有限公司

ZMYND10 Rabbit Polyclonal Antibody (Center)

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产品基本信息

产品货号

BD-PB0999

产品名称

ZMYND10 Rabbit Polyclonal Antibody (Center)

别名

Zinc finger MYND domain-containing protein 10, Protein BLu, ZMYND10, BLU

类别

常规抗体

推荐应用

反应种属

Human

Human Gene ID

NP_056980.2

Human Swissprot No.

O75800

特异性

This ZMYND10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 321-348 amino acids from the Central region of human ZMYND10.

稀释度

WB~~1:1000;IHC-P~~1:100~500;FC~~1:10~50

预测分子量

50kDa

同种型

Rabbit Ig

背景介绍

BLU is a candidate tumor suppressor gene, that spans 4.5 kb on 3p21.3. It encodes a 50 kd protein, which is commonly found in transcription repressors. It is suspected that BLU has a function in cell cycle progression. BLU is a stress-responsive gene regulated by E2F.12 It is commonly found to be downregulated in non-small cell lung cancer, esophagus squamous cell carcinoma and nasopharyngeal carcinoma (NPC).

细胞定位

Cytoplasm {ECO:0000250|UniProtKB:Q6AXZ5}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriolar satellite {ECO:0000250|UniProtKB:Q6AXZ5}. Apical cell membrane {ECO:0000250|UniProtKB:Q99ML0}. Dynein axonemal particle {ECO:0000250|UniProtKB:Q5FWU8}

期货

现货

纯化

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

ZMYND10 Antibody (Center) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the ZMYND10 antibody detected the ZMYND10 protein (arrow).

ZMYND10 Antibody (Center)immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of ZMYND10 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.

ZMYND10 Antibody (Center) flow cytometric analysis of CEM cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.