产品名称
TRIM33 Rabbit Polyclonal Antibody (C-term)
别名
E3 ubiquitin-protein ligase TRIM33, 632-, Ectodermin homolog, RET-fused gene 7 protein, Protein Rfg7, Transcription intermediary factor 1-gamma, TIF1-gamma, Tripartite motif-containing protein 33, TRIM33, KIAA1113, RFG7, TIF1G
Human Gene ID
NP_056990.3;NP_148980.2
Human Swissprot No.
Q9UPN9
特异性
This TRIM33 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1095-1125 amino acids from the C-terminal region of human TRIM33.
背景介绍
The protein encoded by this gene is thought to be a
transcriptional corepressor. However, molecules that interact with
this protein have not yet been identified. The protein is a member
of the tripartite motif family. This motif includes three
zinc-binding domains, a RING, a B-box type 1 and a B-box type 2,
and a coiled-coil region. Three alternatively spliced transcript
variants for this gene have been described, however, the
full-length nature of one variant has not been determined.
组织表达
Expressed in stem cells at the bottom of the crypts of the colon (at protein level). Expressed in colon adenomas and adenocarcinomas (at protein level). Expressed in brain, lung, liver, spleen, thymus, prostate, kidney, testis, heart, placenta, pancreas, small intestine, ovary, colon, skeletal muscle and hematopoietic progenitors
细胞定位
Nucleus. Note=In discrete nuclear dots resembling nuclear bodies.
纯化
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
