BD-PB0986-EIF5AL1 Rabbit Polyclonal Antibody (C-term)-现货抗体产品库武汉枢密脑科学技术有限公司

EIF5AL1 Rabbit Polyclonal Antibody (C-term)

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产品基本信息

产品货号

BD-PB0986

产品名称

EIF5AL1 Rabbit Polyclonal Antibody (C-term)

别名

Eukaryotic translation initiation factor 5A-1-like, eIF-5A-1-like, eIF-5A1-like, Eukaryotic initiation factor 5A isoform 1-like, EIF5AL1

类别

常规抗体

推荐应用

反应种属

Human

Human Gene ID

NP_001093162.1

Human Swissprot No.

Q6IS14

特异性

This EIF5AL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 94-122 amino acids from the C-terminal region of human EIF5AL1.

稀释度

IHC-P~~1:100~500;WB~~1:1000;IF~~1:10~50

预测分子量

17kDa

同种型

Rabbit Ig

背景介绍

EIF5AL1is a mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. Functions as a regulator of apoptosis. Mediates effects of polyamines on neuronal process extension and survival. May play an important role in brain development and function, and in skeletal muscle stem cell differentiation (By similarity).

细胞定位

Cytoplasm. Nucleus. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Nucleus, nuclear pore complex. Note=Hypusine modification promotes the nuclear export and cytoplasmic localization and there was a dynamic shift in the localization from predominantly cytoplasmic to primarily nuclear under apoptotic inducing conditions.

期货

现货

纯化

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

EIF5AL1 Antibody (C-term)immunohistochemistry analysis in formalin fixed and paraffin embedded human uterus tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of EIF5AL1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.

EIF5AL1 Antibody (C-term) western blot analysis in Ramos,A2058 cell line lysates (35ug/lane).This demonstrates the EIF5AL1 antibody detected the EIF5AL1 protein (arrow).

Confocal immunofluorescent analysis of EIF5AL1 Antibody (C-term) with A2058 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). Actin filaments have been labeled with Alexa Fluor 555 phalloidin (red).DAPI was used to stain the cell nuclear (blue).