BD-PB0940-ITGA8 Rabbit Polyclonal Antibody (C-term)-现货抗体产品库武汉枢密脑科学技术有限公司

ITGA8 Rabbit Polyclonal Antibody (C-term)

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产品基本信息

产品货号

BD-PB0940

产品名称

ITGA8 Rabbit Polyclonal Antibody (C-term)

别名

Integrin alpha-8, Integrin alpha-8 heavy chain, Integrin alpha-8 light chain, ITGA8

类别

常规抗体

推荐应用

反应种属

Human, Mouse

Human Gene ID

NP_003629.1

Human Swissprot No.

P53708

特异性

This ITGA8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1025-1053 amino acids from the C-terminal region of human ITGA8.

稀释度

WB~~1:2000

预测分子量

117kDa

同种型

Rabbit Ig

背景介绍

Integrin alpha-8/beta-1 functions in the genesis of kidney and probably of other organs by regulating the recruitment of mesenchymal cells into epithelial structures. It recognizes the sequence R-G-D in a wide array of ligands including TNC, FN1, SPP1 TGFB1, TGFB3 and VTN. NPNT is probably its functional ligand in kidney genesis. Neuronal receptor for TNC it mediates cell-cell interactions and regulates neurite outgrowth of sensory and motor neurons.

组织表达

Expressed in mesenchymal cells, including alveolar myofibroblasts, kidney mesangial cells and hepatic stellar cells and vascular and visceral smooth muscle (at protein level)

细胞定位

Membrane; Single- pass type I membrane protein. Cell membrane

期货

现货

纯化

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Anti-ITGA8 Antibody (C-term) at 1:2000 dilution + K562 whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 117 kDa Blocking/Dilution buffer: 5% NFDM/TBST.

All lanes : Anti-ITGA8 Antibody (C-term) at 1:2000 dilution Lane 1: Raji whole cell lysate Lane 2: 293 whole cell lysate Lane 3: LNCaP whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 117 kDa Blocking/Dilution buffer: 5% NFDM/TBST.