产品名称
K22O Rabbit Polyclonal Antibody
蛋白名称
Keratin, type II cytoskeletal 2 oral (Cytokeratin-2P) (CK-2P) (K2P) (Keratin-76) (K76) (Type-II keratin Kb9)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q01546
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q01546/entry
Mouse Swissprot No.
Q3UV17
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q3UV17
免疫原
Synthesized peptide derived from human protein . at AA range: 220-300
特异性
K22O Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
Keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into epithelial keratins and hair keratins. The type II keratins are clustered in a region of chromosome 12q13. [provided by RefSeq, Jun 2009],
细胞定位
nucleus,intermediate filament,keratin filament,extracellular exosome,
功能
developmental stage:Synthesized during maturation of epidermal keratinocytes.,function:Probably contributes to terminal cornification.,miscellaneous:There are two types of cytoskeletal and microfibrillar keratin: I (acidic; 40-55 kDa) and II (neutral to basic; 56-70 kDa).,sequence caution:Translated as Glu.,similarity:Belongs to the intermediate filament family.,subunit:Heterotetramer of two type I and two type II keratins.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
