BD-PB0897-KRT73 Rabbit Polyclonal Antibody (C-term)-现货抗体产品库武汉枢密脑科学技术有限公司

KRT73 Rabbit Polyclonal Antibody (C-term)

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产品基本信息

产品货号

BD-PB0897

产品名称

KRT73 Rabbit Polyclonal Antibody (C-term)

别名

Keratin, type II cytoskeletal 73, Cytokeratin-73, CK-73, Keratin-73, K73, Type II inner root sheath-specific keratin-K6irs3, Type-II keratin Kb36, KRT73, K6IRS3, KB36, KRT6IRS3

类别

常规抗体

推荐应用

反应种属

Human

Human Gene ID

NP_778238.1

Human Swissprot No.

Q86Y46

特异性

This KRT73 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 493-522 amino acids from the C-terminal region of human KRT73.

稀释度

WB~~1:1000;IHC-P~~1:100~500

预测分子量

59kDa

同种型

Rabbit Ig

背景介绍

Keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into epithelial keratins and hair keratins. This gene encodes a protein that is expressed in the inner root sheath of hair follicles. The type II keratins are clustered in a region of chromosome 12q13.

组织表达

Highly expressed in hair follicles from scalp. In hair, it is specifically present in the inner root sheath (IRS) of the hair follicle. Present in the IRS cuticle, but not in Henle or Huxley layers of the IRS. In the IRS cuticle, it is expressed between the lowermost bulb region of the cuticle and the region where Henle cells undergo abrupt terminal differentiation. Detected up to the uppermost cortex region where cuticle cells terminally differentiate (at protein level).

期货

现货

纯化

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

KRT73 Antibody (C-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the KRT73 antibody detected the KRT73 protein (arrow).

KRT73 Antibody (C-term)immunohistochemistry analysis in formalin fixed and paraffin embedded m.heart tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of KRT73 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.