BD-PB0887-ETFA Rabbit Polyclonal Antibody (C-term)-现货抗体产品库武汉枢密脑科学技术有限公司

ETFA Rabbit Polyclonal Antibody (C-term)

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产品基本信息

产品货号

BD-PB0887

产品名称

ETFA Rabbit Polyclonal Antibody (C-term)

别名

Electron transfer flavoprotein subunit alpha, mitochondrial, Alpha-ETF, ETFA

类别

常规抗体

推荐应用

反应种属

Human, Mouse

Human Gene ID

NP_000117.1;NP_001121188.1

Human Swissprot No.

P13804

特异性

This ETFA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 276-304 amino acids from the C-terminal region of human ETFA.

稀释度

IHC-P~~1:100~500;FC~~1:10~50;WB~~1:1000

预测分子量

35kDa

同种型

Rabbit Ig

背景介绍

ETFA participates in catalyzing the initial step of the mitochondrial fatty acid beta-oxidation. It shuttles electrons between primary flavoprotein dehydrogenases and the membrane-bound electron transfer flavoprotein ubiquinone oxidoreductase. Defects in electron-transfer-flavoprotein have been implicated in type II glutaricaciduria in which multiple acyl-CoA dehydrogenase deficiencies result in large excretion of glutaric, lactic, ethylmalonic, butyric, isobutyric, 2-methyl-butyric, and isovaleric acids. Two transcript variants encoding different isoforms have been found for this gene.

细胞定位

Mitochondrion matrix.

期货

现货

纯化

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

ETFA Antibody (C-term)immunohistochemistry analysis in formalin fixed and paraffin embedded human skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of ETFA Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.

ETFA Antibody (C-term) flow cytometric analysis of Ramos cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

ETFA Antibody (C-term) western blot analysis in K562 cell line and mouse liver tissue lysates (35ug/lane).This demonstrates the ETFA antibody detected the ETFA protein (arrow).