产品名称
TMC2 Rabbit Polyclonal Antibody
基因名称
TMC2 C20orf145 UNQ907/PRO1928
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/117532
Human Swissprot No.
Q8TDI7
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q8TDI7/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/192140
Mouse Swissprot No.
Q8R4P4
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q8R4P4
免疫原
Synthesized peptide derived from human TMC2 AA range: 705-755
特异性
This antibody detects endogenous levels of TMC2 at Human/Mouse
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a transmembrane protein that is necesssary for mechanotransduction in cochlear hair cells of the inner ear. Mutations in this gene may underlie hereditary disorders of balance and hearing. [provided by RefSeq, Aug 2015],
组织表达
Detected in fetal cochlea.
细胞定位
Cell membrane ; Multi-pass membrane protein . Localized to the stereocilia of the cochlear hair cells. .
功能
function:May be required for the normal function of cochlear hair cells.,similarity:Belongs to the TMC family.,tissue specificity:Detected in fetal cochlea.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.