BD-PB0860-JMJD5 Rabbit Polyclonal Antibody (N-term)-现货抗体产品库武汉枢密脑科学技术有限公司

JMJD5 Rabbit Polyclonal Antibody (N-term)

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产品基本信息

产品货号

BD-PB0860

产品名称

JMJD5 Rabbit Polyclonal Antibody (N-term)

别名

Lysine-specific demethylase 8, JmjC domain-containing protein 5, Jumonji domain-containing protein 5, KDM8, JMJD5

类别

常规抗体

推荐应用

反应种属

Human

Human Gene ID

NP_001138820.1;NP_079049.2

Human Swissprot No.

Q8N371

特异性

This JMJD5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 36-63 amino acids from the N-terminal region of human JMJD5.

稀释度

WB~~1:1000

预测分子量

47kDa

同种型

Rabbit Ig

背景介绍

This gene likely encodes a histone lysine demethylase. Studies of a similar protein in mouse indicate a potential role for this protein as a tumor suppressor. Alternatively spliced transcript variants have been described.

组织表达

Weakly expressed in most cells. Highly expressed in breast cancer cells (PubMed:20457893). Expressed in embryonic stem cells (PubMed:24740926).

细胞定位

Nucleus. Chromosome Note=Colocalizes with trimethylated 'Lys-9' of histone H3 (H3K9me3)

期货

现货

纯化

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

All lanes : Anti-JMJD5 Antibody (N-term) at 1:1000 dilution Lane 1: A549 whole cell lysate Lane 2: Hela whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 47 kDa Blocking/Dilution buffer: 5% NFDM/TBST.

Western blot analysis of JMJD5 (arrow) using rabbit polyclonal JMJD5 Antibody (N-term). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the JMJD5 gene.