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P5F1B Rabbit Polyclonal Antibody (C-term)

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产品基本信息

产品货号
BD-PB0838
产品名称
P5F1B Rabbit Polyclonal Antibody (C-term)
别名
Putative POU domain, class 5, transcription factor 1B, Oct4-pg1, Octamer-binding protein 3-like, Octamer-binding transcription factor 3-like, POU5F1B
类别
常规抗体
推荐应用
WB
反应种属
Human
Human Gene ID
NP_001153014.1
Human Swissprot No.
Q06416
特异性
This P5F1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 214-242 amino acids from the C-terminal region of human P5F1B.
稀释度
WB~~1:1000;FC~~1:10~50
预测分子量
39kDa
同种型
Rabbit Ig
背景介绍
This intronless gene was thought to be a transcribed pseudogene of POU class 5 homeobox 1, however, it has been reported that this gene can encode a functional protein. The encoded protein is nearly the same length as and highly similar to the POU class 5 homeobox 1 transcription factor, has been shown to be a weak transcriptional activator and may play a role in carcinogenesis and eye development.
组织表达
Detected at the mRNA level in several cancer tissues (breast, uterine cervix, lung, thyroid gland, esophagus, colon, urinary bladder, and glioma), but absent in normal tissues
细胞定位
Nucleus {ECO:0000255|PROSITE-ProRule:PRU00108, ECO:0000255|PROSITE-ProRule:PRU00530, ECO:0000269|PubMed:18949397}
期货
现货
纯化
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

P5F1B Antibody (C-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the P5F1B antibody detected the P5F1B protein (arrow).

P5F1B Antibody (C-term) flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

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