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GNMT Rabbit Polyclonal Antibody (C-term)

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产品基本信息

产品货号
BD-PB0828
产品名称
GNMT Rabbit Polyclonal Antibody (C-term)
别名
Glycine N-methyltransferase, GNMT
类别
常规抗体
推荐应用
WB
反应种属
Human
Human Gene ID
NP_061833.1
Human Swissprot No.
Q14749
特异性
This GNMT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 218-248 amino acids from the C-terminal region of human GNMT.
稀释度
WB~~1:1000
预测分子量
33kDa
同种型
Rabbit Ig
背景介绍
Glycine N-methyltransferase catalyzes the synthesis of N-methylglycine (sarcosine) from glycine using S-adenosylmethionine (AdoMet) as the methyl donor. GNMT acts as an enzyme to regulate the ratio of S-adenosylmethionine to S-adenosylhomocysteine (AdoHcy) and participates in the detoxification pathway in liver cells.
组织表达
Abundant in liver.
细胞定位
Cytoplasm.
期货
现货
纯化
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Anti-GNMT Antibody (C-term) at 1:1000 dilution + human pancreas lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 33 kDa Blocking/Dilution buffer: 5% NFDM/TBST.

Western blot analysis of anti-GNMT Pab in CEM cell line tissue lysate (35ug/lane).GNMT(arrow) was detected using the purified Pab.

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